Long-Term Deterioration of Kidney Allograft Function
نویسندگان
چکیده
منابع مشابه
Exome Sequencing and Prediction of Long-Term Kidney Allograft Function
Current strategies to improve graft outcome following kidney transplantation consider information at the human leukocyte antigen (HLA) loci. Cell surface antigens, in addition to HLA, may serve as the stimuli as well as the targets for the anti-allograft immune response and influence long-term graft outcomes. We therefore performed exome sequencing of DNA from kidney graft recipients and their ...
متن کاملLong term effects of kidney donation on blood pressure and kidney function of donors
Introduction: Kidney transplantation from a live donor has many advantages, but the donor should undergo a major surgery and accept potential morbidity and mortality. In this study, we evaluated the long term effects of nephrectomy on renal function and blood pressure of kidney donors. Methods: In this cross-sectional study, we assessed 195 kidney donors. The controls were 100 healthy individu...
متن کاملProtecting single-kidney allografts from long-term functional deterioration.
In the past decade, the short-term results of renal transplant surgery have dramatically improved, and 1 -yr graft survival for cadaveric kidneys is now more than 80%, approaching 90 to 95% for living related donor transplants (1 ,2). Better shortterm results, however, have not been paralleled by an acceptable improvement in long-term allograft survival ( I ),so that, after the first year, the ...
متن کاملLong-term CD4 lymphopenia is associated with accelerated decline of kidney allograft function.
BACKGROUND Persistent CD4 T-cell lymphopenia after kidney transplantation has been associated with an increased occurrence of opportunistic infections, malignancies and even mortality, but studies have focussed only on the first few years after kidney transplantation. In this study, we investigated the risk factors and clinical significance of long-term profound CD4 lymphopenia detected ≥10 yea...
متن کاملEffect of CTLA-4 gene polymorphisms on long-term kidney allograft function in Han Chinese recipients
Single nucleotide polymorphisms (SNPs) of cytotoxic T lymphocyte associated antigen-4 gene (CTLA-4) have been associated with graft rejection and long-term clinical outcome after organ transplantation. Our aim was to examine the association between CTLA-4 SNPs (rs733618, rs4553808, rs5742909, rs231775, rs3087243) and long-term allograft function in Chinese renal transplant recipients. Genotypin...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: American Journal of Transplantation
سال: 2005
ISSN: 1600-6135,1600-6143
DOI: 10.1111/j.1600-6143.2005.00853.x